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  • Tianeptine Sulfate

    Tianeptine Sulfate is a modified version of the tricyclic antidepressant tianeptine, known for its mood-enhancing, anxiolytic, and neuroprotective properties. Unlike its sodium counterpart, the sulfate form offers a more stable release and a longer half-life, resulting in prolonged effects and fewer side effects related to dose frequency.
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    • Tianeptine Sulfate is a modified version of the tricyclic antidepressant tianeptine, known for its mood-enhancing, anxiolytic, and neuroprotective properties. Unlike its sodium counterpart, the sulfate form offers a more stable release and a longer half-life, resulting in prolonged effects and fewer side effects related to dose frequency.
      1. Antidepressant Effects: Tianeptine is primarily used to alleviate symptoms of depression. It has been shown to modulate glutamatergic activity and enhance serotonin uptake, which helps in mood stabilization and reducing depressive symptoms without the common side effects associated with other antidepressants.
      2. Anxiolytic Properties: It is also used to reduce anxiety and stress. Tianeptine affects the HPA (hypothalamic-pituitary-adrenal) axis, which helps in reducing stress and anxiety levels. This makes it beneficial for people suffering from generalized anxiety disorder and post-traumatic stress disorder (PTSD).
      3. Neuroprotective Effects: Tianeptine has shown potential in protecting the brain from stress-induced damage. It promotes neuroplasticity and supports cognitive function, which may be beneficial in conditions like Alzheimer’s disease and other neurodegenerative disorders.
      4. Pain Management: There is evidence that tianeptine can be effective in managing chronic pain conditions, particularly neuropathic pain, without the common drawbacks of tolerance or withdrawal symptoms associated with opioid-based pain management treatments.
      5. Mood Stabilization: Tianeptine may provide a more stable mood experience compared to other antidepressants, with fewer peaks and troughs in efficacy.
    • Usage Amount Frequency Notes
      Standard 10-20mg 1 times daily Water-soluble nootropic
      Intensive 20-30mg 1-2 times daily Same as above
      1. 4 Uses of Tianeptine + Mechanisms & Side Effects (Selfhacked)